tag:blogger.com,1999:blog-4384692836709903146.post3448767876335722690..comments2024-03-27T09:55:23.143-07:00Comments on Dispatch from the Digital Health Frontier: The Personal Genome ProjectJohn Halamkahttp://www.blogger.com/profile/04550236129132159307noreply@blogger.comBlogger6125tag:blogger.com,1999:blog-4384692836709903146.post-35044600170992546962008-10-21T15:32:00.000-07:002008-10-21T15:32:00.000-07:00Thanks for all these comments. It is certainly tr...Thanks for all these comments. It is certainly true that the technology is nascent and there may not be a direct relationship between a mutation and a known mechanism of disease. However, I will continue to report everything that is learned about my genome transparently via this blog. Since my cell lines and genome are now available to the world, I expect that many new interesting findings will be circulated.John Halamkahttps://www.blogger.com/profile/04550236129132159307noreply@blogger.comtag:blogger.com,1999:blog-4384692836709903146.post-82804927781474363662008-10-21T11:08:00.000-07:002008-10-21T11:08:00.000-07:00I'd be very careful about believing that you've go...I'd be very careful about believing that you've got alleles that predispose you to one thing or another.<BR/><BR/>What happens a LOT of the time is researchers find what they think is a correlation, and then other people repeat the experiment, on a larger scale, and don't see the correlation. But you tend not to hear about that second experiment.<BR/><BR/>So unless researchers have a proven mechanism down for why that mutation causes that predisposition, take those assesments with a huge grain of salt. I heard a presentation where the researcher suggetsed that 90% of such correlations aren't borne out in larger tests, so that prostate mutation may not be as worrisome as you think.Unknownhttps://www.blogger.com/profile/16435634343642277860noreply@blogger.comtag:blogger.com,1999:blog-4384692836709903146.post-57718041263852748282008-10-20T18:48:00.000-07:002008-10-20T18:48:00.000-07:00JohnYou should be commended for your participation...John<BR/><BR/>You should be commended for your participation. I developed CMT later in life, and having this technology 10 years ago, might have resulted in a significant change in my day to day health care as well as physician input. But then again, the medical community is still learning about CMT and all of it's nuances, so it might have been a bit of a crap shoot at best. Keep up the great work. BIDMC is leading the way with some very cutting edge research as well as offering support and facility accommodations to medical non-profit associations seeking a home for members to congregate. I thank you and everyone else at BIDMC for taking a supportive, as well as a personal role in aggressively pursuing new technologies and embracing those that require additional help.<BR/><BR/>Sincerely,<BR/><BR/>Mark P Boxshus<BR/>New England Support Group Leader<BR/>Charcot Marie Tooth AssociationMark Boxshus "Cookie Doctor"https://www.blogger.com/profile/13404169381490593932noreply@blogger.comtag:blogger.com,1999:blog-4384692836709903146.post-88556298609627950802008-10-20T11:16:00.000-07:002008-10-20T11:16:00.000-07:00The price of testing is falling rapidly from $300 ...The price of testing is falling rapidly from $300 million from Craig Ventner, to $1 million for Jim Watson, to $10,000 for the PGP participants. Hopefully in another a year it will be under $1000. For now, total genome sequencing is limited to research such as PGP.John Halamkahttps://www.blogger.com/profile/04550236129132159307noreply@blogger.comtag:blogger.com,1999:blog-4384692836709903146.post-77891143181931568572008-10-20T09:50:00.000-07:002008-10-20T09:50:00.000-07:00My question is this: How do you get your genetic ...My question is this: How do you get your genetic makeup tested? I've looked at services such as 23andme.com but $399 is out of this college student's budget.Austinhttps://www.blogger.com/profile/15530262791217286906noreply@blogger.comtag:blogger.com,1999:blog-4384692836709903146.post-59334909267990249932008-10-20T09:37:00.000-07:002008-10-20T09:37:00.000-07:00After seeing you at the Red Hat conference this pa...After seeing you at the Red Hat conference this past summer and keeping up on the genome project, I am looking forward to reading the report. I'm not a doctor, so I hope the project releases results in a easy to read language. <BR/><BR/>I work for a major medical diagnostic company, and I have been encouraging our business to invest in this sort of technology to drive certain growth in something that I imagine will be VERY popular.mxgansehttps://www.blogger.com/profile/03688451000253198038noreply@blogger.com